Genes Diseases

Multiple Myeloma: A cancer of the plasma cells.

What is the Multiple Myeloma ?

Multiple myeloma is a type of cancer that affects plasma cells, a type of white blood cell. In this condition, plasma cells become abnormal and multiply uncontrollably, forming tumors in the bone marrow.

What are the symptom of Multiple Myeloma?

Symptoms of multiple myeloma can vary depending on the stage of the disease, but they often include:

  • Bone pain: This is often the first symptom and can be severe, especially in the back, ribs, or pelvis.
  • Fatigue: Feeling tired and weak is common.
  • Frequent infections: Due to the abnormal plasma cells, the immune system may be weakened, leading to frequent infections.
  • Anemia: Low red blood cell count can cause fatigue, shortness of breath, and pale skin.
  • Kidney problems: The abnormal plasma cells can produce substances that damage the kidneys.
  • Calcium levels: High calcium levels in the blood can cause confusion, nausea, and vomiting.

Who can suffer from Multiple Myeloma?

Multiple myeloma can affect anyone, but it is most common in people over the age of 60. The exact cause is unknown, but certain factors may increase the risk, such as age, gender (men are more likely), and race (African Americans are at a higher risk).

What are the type of Multiple Myeloma ?

There are several types of multiple myeloma, based on the genetic changes in the plasma cells:

  • IgG myeloma: The most common type, producing IgG antibodies.
  • IgA myeloma: Producing IgA antibodies.
  • IgD myeloma: Less common, producing IgD antibodies.
  • IgE myeloma: Rare, producing IgE antibodies.
  • Non-secretory myeloma: Plasma cells produce little or no antibodies.

Which diagnostic are available for the Multiple Myeloma ?

·  Blood tests: Can reveal abnormal levels of proteins, calcium, and red blood cells.

·  Urine tests: Can detect the presence of Bence-Jones proteins, a type of abnormal protein produced by myeloma cells.

·  Bone marrow biopsy: A sample of bone marrow is examined for abnormal plasma cells.

·  Imaging tests: X-rays, CT scans, or MRIs can assess bone damage.

What are the treatment of the Multiple Myeloma?

Treatment for multiple myeloma depends on the stage of the disease and the patient’s overall health. Options include:

  • Chemotherapy: Using drugs to kill cancer cells.
  • Radiation therapy: Using high-energy rays to kill cancer cells.
  • Stem cell transplant: Replacing damaged bone marrow with healthy stem cells.
  • Immunotherapy: Using the body’s immune system to fight cancer cells.
  • Targeted therapy: Using drugs that target specific molecules involved in the growth and survival of cancer cells.

Which diet should I take ,if any ?

A healthy diet is essential for people with multiple myeloma. It should be rich in fruits, vegetables, whole grains, and lean protein. Staying hydrated is also important, especially if kidney problems are present.

Which speciality of the doctor will Multiple Myeloma?

Multiple myeloma is typically treated by a hematologist or oncologist, who specializes in blood cancers and their treatments.

In Multiple Myeloma completely curable ?

While multiple myeloma is not currently considered a curable disease, advancements in treatment have significantly improved outcomes. Many patients can achieve long-term remission or even cure, especially when diagnosed early and treated effectively.

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