What is HNPCC Testing?
HNPCC Testing (also known as Lynch Syndrome Testing) is a genetic test to determine if a person carries a gene mutation associated with hereditary nonpolyposis colorectal cancer (HNPCC). HNPCC is a hereditary condition that increases the risk of developing colorectal cancer, as well as other cancers such as endometrial, ovarian, and stomach cancers.
Why HNPCC Testing is required?
HNPCC Testing is important for:
- Individuals with a family history of colorectal cancer, especially if the cancer was diagnosed at a young age or if there were multiple cases in the family.
- Individuals who have already been diagnosed with colorectal cancer, especially if it was diagnosed at a young age or if there were other types of cancer in the family.
- Individuals who are planning to have children, as HNPCC is inherited.
which are the method of HNPCC Testing?
HNPCC Testing typically involves a blood test to analyze DNA for mutations in genes associated with HNPCC. The most common genes tested are MLH1, MSH2, MSH6, and PMS2.
who should go for HNPCC Testing?
As mentioned above, individuals with a family history of colorectal cancer or other cancers associated with HNPCC should consider HNPCC Testing. It’s also recommended for individuals who have already been diagnosed with colorectal cancer, especially if it was diagnosed at a young age.
What are the results of HNPCC Testing?
A positive HNPCC Test result indicates that an individual carries a gene mutation associated with HNPCC. This increases their risk of developing colorectal cancer and other cancers. A negative HNPCC Test result does not guarantee that an individual will not develop cancer, but it does reduce their risk.
What are the components of HNPCC Testing?
HNPCC Testing typically includes:
- DNA analysis for mutations in the MLH1, MSH2, MSH6, and PMS2 genes.
- Genetic counseling to help individuals understand the results of the test and make informed decisions about their healthcare.
