What is Familial Adenomatous Polyposis (FAP) Testing?
FAP testing is a genetic test used to determine if an individual carries the gene mutation associated with familial adenomatous polyposis (FAP). FAP is a hereditary condition characterized by the development of numerous polyps in the large intestine. These polyps can eventually become cancerous, increasing the risk of colon cancer.
Why Familial Adenomatous Polyposis (FAP) Testing is required?
FAP testing is recommended for individuals who have a family history of FAP or who exhibit symptoms such as:
- A large number of polyps in the colon
- Colon cancer at a young age
- A family history of colon cancer
which are the method of Familial Adenomatous Polyposis (FAP) Testing?
FAP testing typically involves a blood sample from which DNA is extracted and analyzed for the gene mutation associated with FAP.
who should go for Familial Adenomatous Polyposis (FAP) Testing?
Individuals with a family history of FAP or those who have been diagnosed with a large number of polyps in the colon should consider FAP testing.
What are the results of Familial Adenomatous Polyposis (FAP) Testing?
A positive FAP test result indicates that an individual carries the gene mutation associated with FAP. A negative result does not guarantee that an individual will not develop FAP, but it significantly reduces the risk.
What are the components of Familial Adenomatous Polyposis (FAP) Testing?
FAP testing primarily focuses on analyzing the APC gene, which is the most commonly mutated gene in FAP. However, other genes associated with FAP, such as MUTYH, may also be tested in some cases.
