What is Lynch Syndrome Testing?
Lynch syndrome is a hereditary condition that increases the risk of developing certain types of cancer, including colorectal cancer. Lynch syndrome testing is a genetic test to determine if a person carries the genes associated with this condition.
Why Lynch Syndrome Testing is required?
If you or a family member has a history of colorectal cancer, especially at a young age, Lynch syndrome testing may be recommended. Early detection and prevention strategies can be implemented if you are diagnosed with Lynch syndrome.
which are the method of Lynch Syndrome Testing?
Lynch syndrome testing typically involves a blood sample. The DNA in the blood is analyzed for mutations in genes associated with Lynch syndrome, such as MLH1, MSH2, MSH6, PMS2, and EPCAM.
who should go for Lynch Syndrome Testing?
Individuals who meet the following criteria may be candidates for Lynch syndrome testing:
- A personal history of colorectal cancer diagnosed before age 50
- A personal history of endometrial cancer diagnosed before age 50
- A family history of colorectal cancer in two or more first-degree relatives
- A family history of other Lynch syndrome-associated cancers (e.g., ovarian, stomach, small intestine, urinary tract, brain)
What are the results of Lynch Syndrome Testing?
Individuals who meet the following criteria may be candidates for Lynch syndrome testing:
- A personal history of colorectal cancer diagnosed before age 50
- A personal history of endometrial cancer diagnosed before age 50
- A family history of colorectal cancer in two or more first-degree relatives
- A family history of other Lynch syndrome-associated cancers (e.g., ovarian, stomach, small intestine, urinary tract, brain)
Results of Lynch Syndrome Testing
A positive Lynch syndrome test result indicates that you carry a gene associated with the condition. A negative result does not guarantee that you won’t develop cancer, but it reduces your risk.
What are the components of Lynch Syndrome Testing?
As mentioned above, Lynch syndrome testing typically involves analyzing genes associated with the condition, including MLH1, MSH2, MSH6, PMS2, and EPCAM.
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